![]() ![]() The sexual dimorphism of all digit ratios (except 2D:3D) is stronger in right than left hand. The digit ratios are lateralized and sexually dimorphic in Greek population. Methods: Male patients ( N 180) who consulted for fertility issues participated in the study. The other digit ratios were also lower in men than women for both hands this difference was statistically significant for all digit ratios of the right hand and for the 2nd to 3rd (2D:3D) and 2nd to 5th (2D:5D) digit ratios of the left hand. Abstract Purpose: To investigate the relationship between the ratio of index to ring finger lengths (2D:4D ratio), reflecting androgen exposure in utero, and reproductive function among men. This difference in 2D:4D ratio between sexes was statistically significant (p < 0.0001 for the right hand and p < 0.001 for the left hand). Fingers' length was measured twice, using an electronic vernier calliper (precision 0.01 mm). A sample of 60 Greek men and 60 Greek women (age range 19-25 years) was selected by random procedures. In view of its clinical importance, this study investigates the 2D:4D ratio, as well as other digit ratios, in Greek population. 2D:4D presents a population variation, which seems to be dependent on geographical position or ethnicity, and may reflect differences in prenatal steroid hormone levels among different ethnic groups. The 2nd to 4th digit ratio (2D:4D) is a sexually dimorphic biometric marker, related to prenatal estrogen and testosterone levels in utero, and determined genetically by the HOX genes. ![]()
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